Epilepsy

Petroff OA, Rothman DL, Behar KL, Mattson RH, Low brain GABA level is associated with poor seizure control, Ann Neurol 40 : 908-11 (1996)

Rothman DL, Petroff OA, Behar KL, Mattson RH, Localized 1H NMR measurements of gamma-aminobutyric acid in human brain in vivo, Proc Natl Acad Sci U S A 90 : 5662-5666 (1993)

Functional studies on brain metabolism

Sibson NR, Mason GF, Shen J, Cline GW, Herskovits AZ, Wall JE, Behar KL, Rothman DL, Shulman RG, In vivo 13C NMR measurement of neurotransmitter glutamate cycling, anaplerosis and TCA cycle flux in rat brain during, J Neurochem 76 : 975-989 (2001)

Sibson NR, Dhankhar A, Mason GF, Rothman DL, Behar KL, Shulman RG, Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity, Proc Natl Acad Sci U S A 95 : 316-21 (1998)

Smith AJ, Blumenfeld H, Behar KL, Rothman DL, Shulman RG, Hyder F, Cerebral energetics and spiking frequency: the neurophysiological basis of fMRI, Proc Natl Acad Sci U S A 99 : 10765-10770 (2002)

Kida I, Kennan RP, Rothman DL, Behar KL, Hyder F, High-resolution CMR(O2) mapping in rat cortex: a multiparametric approach to calibration of BOLD image contrast at 7 Tesla, J Cereb Blood Flow Metab 20 : 847-860 (2000)

Sanacora G, Mason GF, Rothman DL, Hyder F, Ciarcia JJ, Ostroff RB, Berman RM, Krystal JH, Increased Cortical GABA Concentrations in Depressed Patients Receiving ECT, Am J Psychiatry 160 : 577-579 (2003)

Sanacora G, Mason GF, Rothman DL, Behar KL, Hyder F, Petroff OA, Berman RM, Charney DS, Krystal JH, Reduced cortical gamma-aminobutyric acid levels in depressed patients determined by proton magnetic resonance spectroscopy, Arch Gen Psychiatry 56 : 1043-1047 (1999)

Shulman RG, Hyder F, Rothman DL, Biophysical basis of brain activity: implications for neuroimaging, Q Rev Biophys 35: 287-325 (2002)

Rothman DL, Sibson NR, Hyder F, Shen J, Behar KL, Shulman RG, In vivo nuclear magnetic resonance spectroscopy studies of the relationship between the glutamate-glutamine neurotransmitter cycle and functional neuroenergetics, Philos Trans R Soc Lond B Biol Sci 354 : 1165-1177 (1999)

de Graaf RA, Brown PB, McIntyre S, Rothman DL, Nixon TW, Dynamic shim updating (DSU) for multislice signal acquisition, Magn Reson Med 49 : 409-416 (2003)

de Graaf RA, Brown PB, Mason GF, Rothman DL, Behar KL, Detection of [1,6-13C2]-glucose metabolism in rat brain by in vivo 1H-[13C]-NMR spectroscopy, Magn Reson Med 49 : 37-46 (2003)