PET Group Publications

2024

Tau pathology is associated with synaptic density and longitudinal synaptic loss in Alzheimer's disease.Wang J, Huang Q, Chen X, You Z, He K, Guo Q, Huang Y, Yang Y, Lin Z, Guo T, Zhao J, Guan Y, Li B, Xie F. Mol Psychiatry. 2024 Apr 8; 2024 Apr 8. PMID: 38589563.
Does seasonal variation affect the neuroimmune system? A retrospective [(11)C]PBR28 PET study in healthy individuals.Ibrahim W, An J, Yang Y, Cosgrove KP, Matuskey D. Neurosci Lett. 2024 Apr 5; 2024 Apr 5. PMID: 38583505.
Substance use and spine density: a systematic review and meta-analysis of preclinical studies.Oliva HNP, Prudente TP, Nunes EJ, Cosgrove KP, Radhakrishnan R, Potenza MN, Angarita GA. Mol Psychiatry. 2024 Apr 2; 2024 Apr 2. PMID: 38561468.
Synaptic density patterns in early Alzheimer's disease assessed by independent component analysis.Fang XT, Raval NR, O'Dell RS, Naganawa M, Mecca AP, Chen MK, van Dyck CH, Carson RE. Brain Commun. 2024; 2024 Mar 26. PMID: 38601916.
APOE ε4 is associated with decreased synaptic density in cognitively impaired participants.He K, Li B, Wang J, Wang Y, You Z, Chen X, Chen H, Li J, Huang Q, Guo Q, Huang YH, Guan Y, Chen K, Zhao J, Deng Y, Xie F. Alzheimers Dement. 2024 Mar 13; 2024 Mar 13. PMID: 38477490.
Author Correction: Synaptic loss and its association with symptom severity in Parkinson's disease.Holmes SE, Honhar P, Tinaz S, Naganawa M, Hilmer AT, Gallezot JD, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis ED, Comley R, Finnema SJ, Carson RE, Matuskey D. NPJ Parkinsons Dis. 2024 Mar 12; 2024 Mar 12. PMID: 38472206.
Imaging a putative marker of brain cortisol regulation in alcohol use disorder.Verplaetse TL, Hillmer AT, Bhatt S, Rusowicz A, Li S, Nabulsi N, Matuskey D, Huang Y, McKee SA, Cosgrove KP. Neurobiol Stress. 2024 Mar; 2024 Jan 21. PMID: 38304303.
The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [(11)C]UCB-J.Toyonaga T, Khattar N, Wu Y, Lu Y, Naganawa M, Gallezot JD, Matuskey D, Mecca AP, Pittman B, Dias M, Nabulsi NB, Finnema SJ, Chen MK, Arnsten A, Radhakrishnan R, Skosnik PD, D'Souza DC, Esterlis I, Huang Y, van Dyck CH, Carson RE. Eur J Nucl Med Mol Imaging. 2024 Mar; 2023 Nov 13. PMID: 37955791.
Synaptic loss and its association with symptom severity in Parkinson's disease.Holmes SE, Honhar P, Tinaz S, Naganawa M, Hilmer AT, Gallezot JD, Dias M, Yang Y, Toyonaga T, Esterlis I, Mecca A, Van Dyck C, Henry S, Ropchan J, Nabulsi N, Louis ED, Comley R, Finnema SJ, Carson RE, Matuskey D. NPJ Parkinsons Dis. 2024 Feb 24; 2024 Feb 24. PMID: 38402233.
Acute Stress Increases Striatal Connectivity With Cortical Regions Enriched for μ and κ Opioid Receptors.Zhukovsky P, Ironside M, Duda JM, Moser AD, Null KE, Dhaynaut M, Normandin M, Guehl NJ, El Fakhri G, Alexander M, Holsen LM, Misra M, Narendran R, Hoye JM, Morris ED, Esfand SM, Goldstein JM, Pizzagalli DA. Biol Psychiatry. 2024 Feb 22; 2024 Feb 22. PMID: 38395372.
Lower dorsal putamen D2/3 receptor availability and amphetamine-induced dopamine release are related to poorer cognitive function in recently abstinent people who smoke and healthy controls.Cheung F, Calakos KC, Gueorguieva R, Hillmer AT, Cosgrove KP, Zakiniaeiz Y. Nicotine Tob Res. 2024 Feb 17; 2024 Feb 17. PMID: 38367211.
First-in-Human Study of (18)F-SynVesT-2: An SV2A PET Imaging Probe with Fast Brain Kinetics and High Specific Binding.Drake LR, Wu Y, Naganawa M, Asch R, Zheng C, Najafzadeh S, Pracitto R, Lindemann M, Li S, Ropchan J, Labaree D, Emery PR, Dias M, Henry S, Nabulsi N, Matuskey D, Hillmer AT, Gallezot JD, Carson RE, Cai Z, Huang Y. J Nucl Med. 2024 Feb 15; 2024 Feb 15. PMID: 38360052.
Intense exercise increases dopamine transporter and neuromelanin concentrations in the substantia nigra in Parkinson's disease.de Laat B, Hoye J, Stanley G, Hespeler M, Ligi J, Mohan V, Wooten DW, Zhang X, Nguyen TD, Key J, Colonna G, Huang Y, Nabulsi N, Patel A, Matuskey D, Morris ED, Tinaz S. NPJ Parkinsons Dis. 2024 Feb 9; 2024 Feb 9. PMID: 38336768.
Predictions about reward outcomes in rhesus monkeys.Huang Y, Chang H, Santos LR, Rosati AG. Behav Neurosci. 2024 Feb; 2023 Dec 7. PMID: 38060026.
Improving SUVR quantification by correcting for radiotracer clearance in tissue.Honhar P, Matuskey D, Carson RE, Hillmer AT. J Cereb Blood Flow Metab. 2024 Feb; 2023 Aug 17. PMID: 37589538.
The associations between synaptic density and "A/T/N" biomarkers in Alzheimer's disease: An (18)F-SynVesT-1 PET/MR study.Li J, Huang Q, Qi N, He K, Li S, Huang L, Pan F, Ren S, Hua F, Huang Y, Guan Y, Guo Q, Zhao J, Xie F. J Cereb Blood Flow Metab. 2024 Jan 31; 2024 Jan 31. PMID: 38295871.
A pilot study to evaluate the effect of CT1812 treatment on synaptic density and other biomarkers in Alzheimer's disease.van Dyck CH, Mecca AP, O'Dell RS, Bartlett HH, Diepenbrock NG, Huang Y, Hamby ME, Grundman M, Catalano SM, Caggiano AO, Carson RE. Alzheimers Res Ther. 2024 Jan 25; 2024 Jan 25. PMID: 38273408.
Preliminary Study of White Matter Abnormalities and Associations With the Metabotropic Glutamate Receptor 5 to Distinguish Bipolar and Major Depressive Disorders.Fan S, Asch RH, Davis MT, DellaGioia N, Cool R, Blumberg HP, Esterlis I. Chronic Stress (Thousand Oaks). 2024 Jan-Dec; 2024 Jan 17. PMID: 38250007.
Relationship between Neuroimaging and Cognition in Frontotemporal Dementia: A [18 F]FDG PET and Structural MRI Study.Cayir S, Volpi T, Toyonaga T, Gallezot JD, Yanghong Y, Sadabad FE, Mulnix T, Mecca AP, Fesharaki-Zadeh A, Matuskey D. Res Sq. 2024 Jan 15; 2024 Jan 15. PMID: 38313264.
A Review on Low-Dose Emission Tomography Post-Reconstruction Denoising with Neural Network Approaches.Bousse A, Kandarpa VSS, Shi K, Gong K, Lee JS, Liu C, Visvikis D. ArXiv. 2024 Jan 15; 2024 Jan 15. PMID: 38313194.
The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications.Peltier MR, Verplaetse TL, Altemus M, Zakiniaeiz Y, Ralevski EA, Mineur YS, Gueorguieva R, Picciotto MR, Cosgrove KP, Petrakis I, McKee SA. Front Neuroendocrinol. 2024 Jan 4; 2024 Jan 4. PMID: 38184208.
Evaluation of a First PET Tracer Suitable for Imaging the Sigma-2 Receptor in the Brain of Nonhuman Primates.Alluri SR, Zheng M, Holden D, Zhang Y, Zhang L, Felchner Z, Li S, Ropchan J, Carson R, Jia H, Huang Y. Mol Pharm. 2024 Jan 1; 2023 Nov 28. PMID: 38013422.
Assessment of Gray Matter Microstructure and Synaptic Density in Alzheimer's Disease: A Multimodal Imaging Study With DTI and SV2A PET.Silva-Rudberg JA, Salardini E, O'Dell RS, Chen MK, Ra J, Georgelos JK, Morehouse MR, Melino KP, Varma P, Toyonaga T, Nabulsi NB, Huang Y, Carson RE, van Dyck CH, Mecca AP. Am J Geriatr Psychiatry. 2024 Jan; 2023 Aug 11. PMID: 37673749.

2023

Daily positive and negative affect during the COVID-19 pandemic.Ivcevic Z, Shen S, Lin S, Cheng D, Probasco R, Silbermann B, Zhang F, Lin X, Brackett M. Front Psychol. 2023; 2024 Jan 8. PMID: 38259529.
Markerless head motion tracking and event-by-event correction in brain PET.Zeng T, Lu Y, Jiang W, Zheng J, Zhang J, Gravel P, Wan Q, Fontaine K, Mulnix T, Jiang Y, Yang Z, Revilla EM, Naganawa M, Toyonaga T, Henry S, Zhang X, Cao T, Hu L, Carson RE. Phys Med Biol. 2023 Dec 12; 2023 Dec 12. PMID: 37983915.
SLIC-Occ: functional segmentation of occupancy images improves precision of EC(50) images.Ibrahimy A, Hoye J, Wu H, de Laat B, Kim SJ, Wilson DL, Morris ED. EJNMMI Phys. 2023 Dec 11; 2023 Dec 11. PMID: 38079001.
Dose reduction in dynamic synaptic vesicle glycoprotein 2A PET imaging using artificial neural networks.Li A, Yang B, Naganawa M, Fontaine K, Toyonaga T, Carson RE, Tang J. Phys Med Biol. 2023 Dec 8; 2023 Dec 8. PMID: 37857316.
Ketamine and the neurobiology of depression: Toward next-generation rapid-acting antidepressant treatments.Krystal JH, Kaye AP, Jefferson S, Girgenti MJ, Wilkinson ST, Sanacora G, Esterlis I. Proc Natl Acad Sci U S A. 2023 Dec 5; 2023 Nov 27. PMID: 38011560.
FedFTN: Personalized federated learning with deep feature transformation network for multi-institutional low-count PET denoising.Zhou B, Xie H, Liu Q, Chen X, Guo X, Feng Z, Hou J, Zhou SK, Li B, Rominger A, Shi K, Duncan JS, Liu C. Med Image Anal. 2023 Dec; 2023 Oct 6. PMID: 37827110.
Evaluating infusion methods and simplified quantification of synaptic density in vivo with [(11)C]UCB-J and [(18)F]SynVesT-1 PET.Asch RH, Naganawa M, Nabulsi N, Huan Y, Esterlis I, Carson RE. J Cereb Blood Flow Metab. 2023 Dec; 2023 Sep 5. PMID: 37669455.
Examining mGlu5 Receptor Availability as a Predictor of Vulnerability to PTSD: An [(18)F]FPEB and PET Study in Male and Female Rats.Asch RH, Fowles K, Pietrzak RH, Taylor JR, Esterlis I. Chronic Stress (Thousand Oaks). 2023 Jan-Dec; 2023 Nov 21. PMID: 38024327.
An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?Volpi T, Maccioni L, Colpo M, Debiasi G, Capotosti A, Ciceri T, Carson RE, DeLorenzo C, Hahn A, Knudsen GM, Lammertsma AA, Price JC, Sossi V, Wang G, Zanotti-Fregonara P, Bertoldo A, Veronese M. EJNMMI Res. 2023 Nov 10; 2023 Nov 10. PMID: 37947880.
Intrathecal delivery of nanoparticle PARP inhibitor to the cerebrospinal fluid for the treatment of metastatic medulloblastoma.Khang M, Lee JH, Lee T, Suh HW, Lee S, Cavaliere A, Rushing A, Geraldo LH, Belitzky E, Rossano S, de Feyter HM, Shin K, Huttner A, Roussel MF, Thomas JL, Carson RE, Marquez-Nostra B, Bindra RS, Saltzman WM. Sci Transl Med. 2023 Nov; 2023 Nov 1. PMID: 37910601.
TAI-GAN: Temporally and Anatomically Informed GAN for Early-to-Late Frame Conversion in Dynamic Cardiac PET Motion Correction.Guo X, Shi L, Chen X, Zhou B, Liu Q, Xie H, Liu YH, Palyo R, Miller EJ, Sinusas AJ, Spottiswoode B, Liu C, Dvornek NC. Simul Synth Med Imaging. 2023 Oct; 2023 Oct 7. PMID: 38464964.
Fast Reconstruction for Deep Learning PET Head Motion Correction.Zeng T, Zhang J, Lieffrig EV, Cai Z, Chen F, You C, Naganawa M, Lu Y, Onofrey JA. Med Image Comput Comput Assist Interv. 2023 Oct; 2023 Oct 1. PMID: 38174207.
Suicidal Thoughts and Behaviors in Older U.S. Military Veterans: Results From the National Health and Resilience in Veterans Study.Fischer IC, Nichter B, Aunon FM, Feldman DB, Levy BR, Esterlis I, Pietrzak RH. Am J Geriatr Psychiatry. 2023 Oct; 2023 Apr 29. PMID: 37211498.
Deep-learning-based methods of attenuation correction for SPECT and PET.Chen X, Liu C. J Nucl Cardiol. 2023 Oct; 2022 Jun 9. PMID: 35680755.
Development of a Highly Specific (18)F-Labeled Radioligand for Imaging of the Sigma-2 Receptor in Brain Tumors.Wang T, Wang J, Chen L, Zhang X, Mou T, An X, Zhang J, Zhang X, Deuther-Conrad W, Huang Y, Jia H. J Med Chem. 2023 Sep 28; 2023 Sep 13. PMID: 37704582.
First-in-Human PET Imaging of [(18)F]SDM-4MP3: A Cautionary Tale.Desmond KL, Lindberg A, Garcia A, Tong J, Harkness MB, Dobrota E, Smart K, Uribe C, Meyer JH, Houle S, Strafella AP, Li S, Huang Y, Vasdev N. Mol Imaging. 2023; 2023 Sep 8. PMID: 37719326.
Relationships of in vivo brain norepinephrine transporter and age, BMI, and gender.Koohsari S, Sadabad FE, Pittman B, Gallezot JD, Carson RE, van Dyck CH, Li CR, Potenza MN, Matuskey D. Synapse. 2023 Sep; 2023 Jun 29. PMID: 37382240.
Multimodality Imaging of Aortic Valve Calcification and Function in a Murine Model of Calcific Aortic Valve Disease and Bicuspid Aortic Valve.Ahmad AA, Ghim M, Toczek J, Neishabouri A, Ojha D, Zhang Z, Gona K, Raza MZ, Jung JJ, Kukreja G, Zhang J, Guerrera N, Liu C, Sadeghi MM. J Nucl Med. 2023 Sep; 2023 Jun 15. PMID: 37321825.
Developing Researchers with Expertise in Sex as a Biological Variable through SCORE Career Enhancement Core Center Programs.Zakiniaeiz Y, Peltier MR, Mineur YS, Gueorguieva R, Picciotto MR, Petrakis I, Cosgrove KP, McKee SA. J Womens Health (Larchmt). 2023 Aug. PMID: 37585509.
Imaging the brain's immune response to alcohol with [(11)C]PBR28 TSPO Positron Emission Tomography.Raval NR, Angarita G, Matuskey D, Miller R, Drake LR, Kapinos M, Nabulsi N, Huang Y, Carson RE, O'Malley SS, Cosgrove KP, Hillmer AT. Mol Psychiatry. 2023 Aug; 2023 Aug 2. PMID: 37532797.
Perceived mental health of psychosocial support professionals in Ukraine.Kang H, Esterlis I, Chobanian AV, Boriak O, Pietrzak RH, Vus V. Psychiatry Res. 2023 Aug; 2023 Jun 20. PMID: 37352745.
DuSFE: Dual-Channel Squeeze-Fusion-Excitation co-attention for cross-modality registration of cardiac SPECT and CT.Chen X, Zhou B, Xie H, Guo X, Zhang J, Duncan JS, Miller EJ, Sinusas AJ, Onofrey JA, Liu C. Med Image Anal. 2023 Aug; 2023 May 16. PMID: 37216735.
Differences in Quantification of the Metabotropic Glutamate Receptor 5 Across Bipolar Disorder and Major Depressive Disorder.Holmes SE, Asch RH, Davis MT, DellaGioia N, Pashankar N, Gallezot JD, Nabulsi N, Matuskey D, Sanacora G, Carson RE, Blumberg HP, Esterlis I. Biol Psychiatry. 2023 Jun 15; 2022 Nov 8. PMID: 36764853.
Sex steroid hormone levels associated with dopamine D(2/3) receptor availability in people who smoke cigarettes.Zakiniaeiz Y, Gueorguieva R, Peltier MR, Verplaetse TL, Roberts W, McKee SA, Cosgrove KP. Front Behav Neurosci. 2023; 2023 Jun 9. PMID: 37358969.
A randomized clinical trial of behavioral activation and exposure-based therapy for adults with generalized anxiety disorder.Berg H, Akeman E, McDermott TJ, Cosgrove KT, Kirlic N, Clausen A, Cannon M, Yeh HW, White E, Thompson WK, Choquette EM, Sturycz-Taylor CA, Cochran G, Ramirez S, Martell CR, Wolitzky-Taylor KB, Craske MG, Abelson JL, Paulus MP, Aupperle RL. J Mood Anxiety Disord. 2023 Jun; 2023 Jun 9. PMID: 38384390.
Synaptic Loss in Spinocerebellar Ataxia Type 3 Revealed by SV2A Positron Emission Tomography.Chen Z, Liao G, Wan N, He Z, Chen D, Tang Z, Long Z, Zou G, Peng L, Wan L, Wang C, Peng H, Shi Y, Tang Y, Li J, Li Y, Long T, Hou X, He L, Qiu R, Chen D, Wang J, Guo J, Shen L, Huang Y, Ashizawa T, Klockgether T, Tang B, Zhou M, Hu S, Jiang H. Mov Disord. 2023 Jun; 2023 Apr 6. PMID: 37023261.
Preclinical evaluation of a brain penetrant PARP PET imaging probe in rat glioblastoma and nonhuman primates.Chen B, Ojha DP, Toyonaga T, Tong J, Pracitto R, Thomas MA, Liu M, Kapinos M, Zhang L, Zheng MQ, Holden D, Fowles K, Ropchan J, Nabulsi N, De Feyter H, Carson RE, Huang Y, Cai Z. Eur J Nucl Med Mol Imaging. 2023 Jun; 2023 Feb 28. PMID: 36849748.
In vivo synaptic density loss correlates with impaired functional and related structural connectivity in Alzheimer's disease.Zhang J, Wang J, Xu X, You Z, Huang Q, Huang Y, Guo Q, Guan Y, Zhao J, Liu J, Xu W, Deng Y, Xie F, Li B. J Cereb Blood Flow Metab. 2023 Jun; 2023 Jan 30. PMID: 36718002.
Clustering of KOR PET images separates people with AUD into distinct responses to naltrexone.Hoye J, Key J, de Laat B, Cosgrove KP, Krishnan-Sarin S, Papademetris X, Morris ED. Brain Imaging Behav. 2023 Jun; 2023 Jan 25. PMID: 36695971.
Generation of Whole-Body FDG Parametric K(i) Images from Static PET Images Using Deep Learning.Miao T, Zhou B, Liu J, Guo X, Liu Q, Xie H, Chen X, Chen MK, Wu J, Carson RE, Liu C. IEEE Trans Radiat Plasma Med Sci. 2023 May; 2023 Feb 22. PMID: 37997577.
Reductions in synaptic marker SV2A in early-course Schizophrenia.Yoon JH, Zhang Z, Mormino E, Davidzon G, Minzenberg MJ, Ballon J, Kalinowski A, Hardy K, Naganawa M, Carson RE, Khalighi M, Park JH, Levinson DF, Chin FT. J Psychiatr Res. 2023 May; 2023 Feb 23. PMID: 36934603.
Lower Dopamine D2/3 Receptor Availability is Associated With Worse Verbal Learning and Memory in People Who Smoke Cigarettes.Zakiniaeiz Y, Gueorguieva R, Peltier MR, Roberts W, Verplaetse TL, Burke C, Morris ED, McKee SA, Cosgrove KP. Nicotine Tob Res. 2023 Apr 6. PMID: 36107715.
Inter-pass motion correction for whole-body dynamic PET and parametric imaging.Guo X, Wu J, Chen MK, Liu Q, Onofrey JA, Pucar D, Pang Y, Pigg D, Casey ME, Dvornek NC, Liu C. IEEE Trans Radiat Plasma Med Sci. 2023 Apr; 2022 Dec 8. PMID: 37842204.
(18)F-Labeled o‑aminopyridyl alkynyl radioligands targeting colony-stimulating factor 1 receptor for neuroinflammation imaging.An X, Wang J, Tong L, Zhang X, Fu H, Zhang J, Xie H, Huang Y, Jia H. Bioorg Med Chem. 2023 Apr 1; 2023 Mar 8. PMID: 36933438.
Hot spot imaging in cardiovascular diseases: an information statement from SNMMI, ASNC, and EANM.Sperry BW, Bateman TM, Akin EA, Bravo PE, Chen W, Dilsizian V, Hyafil F, Khor YM, Miller RJH, Slart RHJA, Slomka P, Verberne H, Miller EJ, Liu C. J Nucl Cardiol. 2023 Apr; 2022 Jul 21. PMID: 35864433.
A 3D atlas of functional human brain energetic connectome based on neuropil distribution.Yu Y, Akif A, Herman P, Cao M, Rothman DL, Carson RE, Agarwal D, Evans AC, Hyder F. Cereb Cortex. 2023 Mar 21. PMID: 36104858.
Federated Transfer Learning for Low-dose PET Denoising: A Pilot Study with Simulated Heterogeneous Data.Zhou B, Miao T, Mirian N, Chen X, Xie H, Feng Z, Guo X, Li X, Zhou SK, Duncan JS, Liu C. IEEE Trans Radiat Plasma Med Sci. 2023 Mar; 2022 Jul 27. PMID: 37789946.
Cholinergic system adaptations are associated with cognitive function in people recently abstinent from smoking: a (-)-[(18)F]flubatine PET study.Calakos KC, Hillmer AT, Anderson JM, LeVasseur B, Baldassarri SR, Angarita GA, Matuskey D, Kapinos M, Zheng MQ, Huang Y, Cosgrove KP. Neuropsychopharmacology. 2023 Mar; 2023 Jan 21. PMID: 36681758.
Linking resting-state network fluctuations with systems of coherent synaptic density: A multimodal fMRI and (11)C-UCB-J PET study.Fang XT, Volpi T, Holmes SE, Esterlis I, Carson RE, Worhunsky PD. Front Hum Neurosci. 2023; 2023 Feb 23. PMID: 36908710.
Nicotine Use and Metabotropic Glutamate Receptor 5 in Individuals With Major Depressive and Posttraumatic Stress Disorders.Baldassarri SR, Asch RH, Hillmer AT, Pietrzak RH, DellaGioia N, Esterlis I, Davis MT. Chronic Stress (Thousand Oaks). 2023 Jan-Dec; 2023 Feb 9. PMID: 36843572.
Subjective cognitive difficulties and posttraumatic stress disorder interact to increase suicide risk among middle-aged and older US military veterans.Cations M, Cook JM, Nichter B, Esterlis I, Pietrzak RH. Int Psychogeriatr. 2023 Feb 9; 2023 Feb 9. PMID: 36756753.
Decreased synaptic vesicle glycoprotein 2A binding in a rodent model of familial Alzheimer's disease detected by [(18)F]SDM-16.Zheng C, Toyonaga T, Chen B, Nicholson L, Mennie W, Liu M, Spurrier J, Deluca K, Strittmatter SM, Carson RE, Huang Y, Cai Z. Front Neurol. 2023; 2023 Feb 8. PMID: 36846134.
Investigating CNS distribution of PF-05212377, a P-glycoprotein substrate, by translation of 5-HT(6) receptor occupancy from non-human primates to humans.Sawant-Basak A, Chen L, Lockwood P, Boyden T, Doran AC, Mancuso J, Zasadny K, McCarthy T, Morris ED, Carson RE, Esterlis I, Huang Y, Nabulsi N, Planeta B, Fullerton T. Biopharm Drug Dispos. 2023 Feb; 2023 Mar 13. PMID: 36825693.
Serotonin transporter availability in physically aggressive personality disordered patients: associations with trait and state aggression, and response to fluoxetine.Rosell DR, Slifstein M, Thompson J, Xu X, Perez-Rodriguez MM, McClure MM, Hazlett EA, New AS, Nabulsi N, Huang Y, Carson RE, Siever LS, Abi-Dargham A, Koenigsberg HW. Psychopharmacology (Berl). 2023 Feb; 2023 Jan 14. PMID: 36640190.
Artificial Intelligence in Nuclear Medicine: Opportunities, Challenges, and Responsibilities Toward a Trustworthy Ecosystem.Saboury B, Bradshaw T, Boellaard R, Buvat I, Dutta J, Hatt M, Jha AK, Li Q, Liu C, McMeekin H, Morris MA, Scott PJH, Siegel E, Sunderland JJ, Pandit-Taskar N, Wahl RL, Zuehlsdorff S, Rahmim A. J Nucl Med. 2023 Feb; 2022 Dec 15. PMID: 36522184.
Neurotransmitter transporter occupancy following administration of centanafadine sustained-release tablets: A phase 1 study in healthy male adults.Matuskey D, Gallezot JD, Nabulsi N, Henry S, Torres K, Dias M, Angarita GA, Huang Y, Shoaf SE, Carson RE, Mehrotra S. J Psychopharmacol. 2023 Feb; 2022 Dec 14. PMID: 36515395.
Quantification of intramyocardial blood volume using (99m)Tc-RBC SPECT/CT: a pilot human study.Yousefi H, Shi L, Soufer A, Tsatkin V, Bruni W, Avendano R, Greco K, McMahon D, Thorn S, Miller E, Sinusas A, Liu C. J Nucl Cardiol. 2023 Feb; 2022 Nov 1. PMID: 36319815.
Examining sex differences in responses to footshock stress and the role of the metabotropic glutamate receptor 5: an [(18)F]FPEB and positron emission tomography study in rats.Asch RH, Pothula S, Toyonaga T, Fowles K, Groman SM, Garcia-Milian R, DiLeone RJ, Taylor JR, Esterlis I. Neuropsychopharmacology. 2023 Feb; 2022 Sep 13. PMID: 36100654.
Increasing angular sampling through deep learning for stationary cardiac SPECT image reconstruction.Xie H, Thorn S, Chen X, Zhou B, Liu H, Liu Z, Lee S, Wang G, Liu YH, Sinusas AJ, Liu C. J Nucl Cardiol. 2023 Feb; 2022 May 4. PMID: 35508796.
In Vivo Imaging and Kinetic Modeling of Novel Glycogen Synthase Kinase-3 Radiotracers [(11)C]OCM-44 and [(18)F]OCM-50 in Non-Human Primates.Smart K, Zheng MQ, Holden D, Felchner Z, Zhang L, Han Y, Ropchan J, Carson RE, Vasdev N, Huang Y. Pharmaceuticals (Basel). 2023 Jan 28; 2023 Jan 28. PMID: 37259346.
Joint motion estimation and penalized image reconstruction algorithm with anatomical priors for gated TOF-PET/CT.Tsai YJ, Liu C. Phys Med Biol. 2023 Jan 13; 2023 Jan 13. PMID: 36549009.
Principal component analysis of synaptic density measured with [(11)C]UCB-J PET in early Alzheimer's disease.O'Dell RS, Higgins-Chen A, Gupta D, Chen MK, Naganawa M, Toyonaga T, Lu Y, Ni G, Chupak A, Zhao W, Salardini E, Nabulsi NB, Huang Y, Arnsten AFT, Carson RE, van Dyck CH, Mecca AP. Neuroimage Clin. 2023; 2023 Jun 22. PMID: 37422964.
Deep-Learning-Based Few-Angle Cardiac SPECT Reconstruction Using Transformer.Xie H, Thorn S, Liu YH, Lee S, Liu Z, Wang G, Sinusas AJ, Liu C. IEEE Trans Radiat Plasma Med Sci. 2023 Jan; 2022 Jun 30. PMID: 37397179.
The metabotropic glutamate receptor 5 as a biomarker for psychiatric disorders.Asch RH, Hillmer AT, Baldassarri SR, Esterlis I. Int Rev Neurobiol. 2023; 2022 Nov 18. PMID: 36868631.
Noninvasive Quantitative PET Imaging in Humans of the Pancreatic Beta-Cell Mass Biomarkers VMAT2 and Dopamine D2/D3 Receptors In Vivo.Bini J, Carson RE, Cline GW. Methods Mol Biol. 2023. PMID: 36507985.
PET imaging of kappa opioid receptors and receptor expression quantified in neuron-derived extracellular vesicles in socially housed female and male cynomolgus macaques.Johnson BN, Kumar A, Su Y, Singh S, Sai KKS, Nader SH, Li S, Reboussin BA, Huang Y, Deep G, Nader MA. Neuropsychopharmacology. 2023 Jan; 2022 Sep 13. PMID: 36100655.
DuDoSS: Deep-learning-based dual-domain sinogram synthesis from sparsely sampled projections of cardiac SPECT.Chen X, Zhou B, Xie H, Miao T, Liu H, Holler W, Lin M, Miller EJ, Carson RE, Sinusas AJ, Liu C. Med Phys. 2023 Jan; 2022 Sep 28. PMID: 36048541.
Imaging synaptic density in depression.Holmes SE, Abdallah C, Esterlis I. Neuropsychopharmacology. 2023 Jan; 2022 Jun 29. PMID: 35768568.

2022

An objective evaluation method for head motion estimation in PET-Motion corrected centroid-of-distribution.Sun C, Revilla EM, Zhang J, Fontaine K, Toyonaga T, Gallezot JD, Mulnix T, Onofrey JA, Carson RE, Lu Y. Neuroimage. 2022 Dec 1; 2022 Oct 17. PMID: 36261057.
Age, gender and body-mass-index relationships with in vivo CB(1) receptor availability in healthy humans measured with [(11)C]OMAR PET.Radhakrishnan R, Worhunsky PD, Zheng MQ, Najafzadeh S, Gallezot JD, Planeta B, Henry S, Nabulsi N, Ranganathan M, Skosnik PD, Pittman B, Cyril D'Souza D, Carson RE, Huang Y, Potenza MN, Matuskey D. Neuroimage. 2022 Dec 1; 2022 Oct 13. PMID: 36243269.
Evaluation of (rac)-, (R)-, and (S)-(18)F-OF-NB1 for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Receptors in Nonhuman Primates.Ahmed H, Zheng MQ, Smart K, Fang H, Zhang L, Emery PR, Gao H, Ropchan J, Haider A, Tamagnan G, Carson RE, Ametamey SM, Huang Y. J Nucl Med. 2022 Dec; 2022 Jun 16. PMID: 35710735.
Cross-vender, cross-tracer, and cross-protocol deep transfer learning for attenuation map generation of cardiac SPECT.Chen X, Hendrik Pretorius P, Zhou B, Liu H, Johnson K, Liu YH, King MA, Liu C. J Nucl Cardiol. 2022 Dec; 2022 Apr 26. PMID: 35474443.
Synaptic density and cognitive performance in Alzheimer's disease: A PET imaging study with [(11) C]UCB-J.Mecca AP, O'Dell RS, Sharp ES, Banks ER, Bartlett HH, Zhao W, Lipior S, Diepenbrock NG, Chen MK, Naganawa M, Toyonaga T, Nabulsi NB, Vander Wyk BC, Arnsten AFT, Huang Y, Carson RE, van Dyck CH. Alzheimers Dement. 2022 Dec; 2022 Feb 17. PMID: 35174954.
Post-reconstruction attenuation correction for SPECT myocardium perfusion imaging facilitated by deep learning-based attenuation map generation.Liu H, Wu J, Shi L, Liu Y, Miller E, Sinusas A, Liu YH, Liu C. J Nucl Cardiol. 2022 Dec; 2021 Oct 20. PMID: 34671940.
Drug characteristics derived from kinetic modeling: combined (11)C-UCB-J human PET imaging with levetiracetam and brivaracetam occupancy of SV2A.Naganawa M, Gallezot JD, Finnema SJ, Maguire RP, Mercier J, Nabulsi NB, Kervyn S, Henry S, Nicolas JM, Huang Y, Chen MK, Hannestad J, Klitgaard H, Stockis A, Carson RE. EJNMMI Res. 2022 Nov 8; 2022 Nov 8. PMID: 36346513.
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex.Hansen JY, Shafiei G, Markello RD, Smart K, Cox SML, Nørgaard M, Beliveau V, Wu Y, Gallezot JD, Aumont É, Servaes S, Scala SG, DuBois JM, Wainstein G, Bezgin G, Funck T, Schmitz TW, Spreng RN, Galovic M, Koepp MJ, Duncan JS, Coles JP, Fryer TD, Aigbirhio FI, McGinnity CJ, Hammers A, Soucy JP, Baillet S, Guimond S, Hietala J, Bedard MA, Leyton M, Kobayashi E, Rosa-Neto P, Ganz M, Knudsen GM, Palomero-Gallagher N, Shine JM, Carson RE, Tuominen L, Dagher A, Misic B. Nat Neurosci. 2022 Nov; 2022 Oct 27. PMID: 36303070.
Systemic inflammation enhances stimulant-induced striatal dopamine elevation in tobacco smokers.Zakiniaeiz Y, Hoye J, Ryan Petrulli J, LeVasseur B, Stanley G, Gao H, Najafzadeh S, Ropchan J, Nabulsi N, Huang Y, Chen MK, Matuskey D, Barron DS, Kelmendi B, Fulbright RK, Hampson M, Cosgrove KP, Morris ED. Brain Behav Immun. 2022 Nov; 2022 Sep 1. PMID: 36058419.
Nicotine Patch Alters Patterns of Cigarette Smoking-Induced Dopamine Release: Patterns Relate to Biomarkers Associated With Treatment Response.Zakiniaeiz Y, Liu H, Gao H, Najafzadeh S, Ropchan J, Nabulsi N, Huang Y, Matuskey D, Chen MK, Cosgrove KP, Morris ED. Nicotine Tob Res. 2022 Oct 17. PMID: 35100429.
Editorial: Translational advances in Alzheimer's, Parkinson's, and other dementia: Molecular mechanisms, biomarkers, diagnosis, and therapies, volume II.Jiang J, Shi K, Huang YH, Hsu CY, Hettie KS, Kung WM. Front Aging Neurosci. 2022; 2022 Oct 10. PMID: 36299613.
Dual-domain self-supervised learning for accelerated non-Cartesian MRI reconstruction.Zhou B, Schlemper J, Dey N, Mohseni Salehi SS, Sheth K, Liu C, Duncan JS, Sofka M. Med Image Anal. 2022 Oct; 2022 Jul 18. PMID: 35926336.
Detection of changes in synaptic density in amyotrophic lateral sclerosis patients using (18) F-SynVesT-1 positron emission tomography.Tang Y, Liu P, Li W, Liu Z, Zhou M, Li J, Yuan Y, Fang L, Wang M, Shen L, Huang Y, Tang B, Wang J, Hu S. Eur J Neurol. 2022 Oct; 2022 Jul 6. PMID: 35708508.
CT-free attenuation correction for dedicated cardiac SPECT using a 3D dual squeeze-and-excitation residual dense network.Chen X, Zhou B, Shi L, Liu H, Pang Y, Wang R, Miller EJ, Sinusas AJ, Liu C. J Nucl Cardiol. 2022 Oct; 2021 Jun 3. PMID: 34085168.
MCP-Net: Inter-frame Motion Correction with Patlak Regularization for Whole-body Dynamic PET.Guo X, Zhou B, Chen X, Liu C, Dvornek NC. Med Image Comput Comput Assist Interv. 2022 Sep; 2022 Sep 16. PMID: 38464686.
PET Image Denoising using a Deep-Learning Method for Extremely Obese Patients.Liu H, Yousefi H, Mirian N, Lin M, Menard D, Gregory M, Aboian M, Boustani A, Chen MK, Saperstein L, Pucar D, Kulon M, Liu C. IEEE Trans Radiat Plasma Med Sci. 2022 Sep; 2021 Dec 2. PMID: 37284026.
A Role for Histone Deacetylases in the Biology and Treatment of Post-Traumatic Stress Disorder: What Do We Know and Where Do We Go from Here?Bonomi RE, Girgenti M, Krystal JH, Cosgrove KP. Complex Psychiatry. 2022 Sep; 2022 Mar 15. PMID: 36545044.
Data Management and Network Architecture Effect on Performance Variability in Direct Attenuation Correction via Deep Learning for Cardiac SPECT: A Feasibility Study.Torkaman M, Yang J, Shi L, Wang R, Miller EJ, Sinusas AJ, Liu C, Gullberg GT, Seo Y. IEEE Trans Radiat Plasma Med Sci. 2022 Sep; 2021 Dec 24. PMID: 36059429.
Virtual high-count PET image generation using a deep learning method.Liu J, Ren S, Wang R, Mirian N, Tsai YJ, Kulon M, Pucar D, Chen MK, Liu C. Med Phys. 2022 Sep; 2022 Aug 13. PMID: 35880541.